구순구개열환자에서의 전신적 선천기형질환에 대한 역학적 연구
문철현, 幸地省子,
소속 상세정보
문철현 ( Moon Cheol-Hyun ) - 가천의과학대학교 길병원 교정과
幸地省子 ( Shoko Kochi ) - 동북대학치학부속병원 악구강기능치료부
KMID : 0362720050430020110
Abstract
구순구개열은 가장 흔히 보는 선천기형중 하나이며1-5) 구순구개열 환자에서 다른 종류의 선천이상을 동반하는 경우를 종종 볼 수 있다. 구순구개열 환자의 치료에 있어 선천 합병기형의 조기 발견과 적절한 처치는 매우 중요한 사항이다.
저자들은 동북대학치학부속병원 악구강기능치료부에서 진료를 받은 구순구개열 환자를 대상으로 선천합병기형에 관한 임상통계적 조사를 실시하였다.
Cleft lip and/or palate is one of the most common congenital abnormalies. And we experience clinically associated anomalies with cleft lip and/or palate most often. For cleft lip and/or palate patients, early finding and early treatment of associated anomalies is very important. A clinico-statistical investigation of the associated congenital anomalies was made on 1456 patients with cleft lip and/or palate who were in Clinics for Maxillo-Oral Disorders, Tohoku University Dental Hospital from January, 1987 to December, 2002.
The following results were obtained.
1. The patients were 761 males and 695 females. Cleft morphology was classified as follows: CL in 437 cases, CLP in 613 cases, CP in 329 cases, SMCP in 72 cases, MC in 5 cases.
2. The associated anomalies were observed in 170 patients, which was a 11.7% incidence rate.
3. Among the associated anomalies, congenital heart disease was the most often observed, followed by extremity malformation, ear malformation, digestive system anomalies and cell(chromosome) anomalies.
4. Congenital heart disease was observed in 50 patients, which was a 3.4% incidence rate. VSD was the most often observed.
5. Extremity malformation was observed in 46 patients, which was a 3.2% incidence rate. Dislocations of hips was the most often observed.
6. Ear malformation was observed in 26 patients, which was a 1.8% incidence rate. Hearing difficulty that is caused by ear anomaly was the most often observed.
7. Digestive system anomaly was observed in 24 patients, which was a 1.6% incidence rate. Hiatal hernia was the most often observed.
8. Of 15 cases were diagnosed as a syndrome, Down? syndrome was observed in 3 cases and Pirre-Robin syndrome in 2, Orofacial digital syndrome in 2.
9. Medication within 1st trimester was observed in 168 patients, which was a 11.5% incidence rate. Out of the 170 associated anomalies patients, 25 patients(14.7%) were found to be medicated patients. Out of the 1286 non-associated anomalies patients, 143 patients(11.1%) were found to be medicated patients. The most common used medicine was antiabortifacient.
키워드
Cleft lip and/or palate;Associated anomalies;Congenital heart disease
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